Multiple sclerosis (MS) is an autoimmune disease that affects the brain and spinal cord (central nervous system). MS attacks axons in the central nervous system protected by myelin, which is commonly referred to as white matter. Multiple sclerosis also damages nerve cell bodies, which are found in the gray matter of the brain, as well as the brain's own axons, spinal cord and optic nerves that transmit visual information from the eye to the brain. As the disease progresses, the outermost layer of the brain, called the cerebral cortex, contracts in a process known as cortical atrophy.
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by injuries to the central nervous system (CNS) that can result in severe physical or cognitive impairment, as well as neurological defects. Although the etiology and pathogenesis of MS remain unclear, the present documents illustrate that the cause of MS is multifactorial and includes genetic predisposition along with environmental factors such as exposure to infectious agents, vitamin deficiencies and smoking. These agents are capable of triggering a cascade of events in the immune system that lead to the death of neuronal cells, accompanied by nerve demyelination and neuronal dysfunction. Conventional therapies for MS are based on the use of anti-inflammatory and immunomodulatory drugs, but these treatments are not capable of stopping the destruction of nerve tissue.
Therefore, other strategies, such as stem cell transplantation, have been proposed for the treatment of MS. In general, it is important for neurologists to know current information about the pathogenesis, etiology, diagnostic criteria, and treatment of MS. Therefore, this topic has been discussed according to recently available information. Nerve cells carry messages between the central nervous system and the organs and limbs of the body.
In multiple sclerosis (MS), nerve cells or neurons are damaged by inflammation and demyelination can occur. Multiple sclerosis is thought to be partly an autoimmune and partly a neurodegenerative condition. For some reason, the body's immune system begins to mistakenly attack the cells of the central nervous system. Initially, the body can repair the damage to a certain extent, but over time nerve cells can begin to die.
Scars form on damaged nerves. This scar tissue is what forms lesions that appear as white regions on MRI scans. Multiple sclerosis is a chronic, unpredictable disease of the central nervous system, which is made up of the brain, spinal cord, and optic nerves. MS is thought to be an immune-mediated disorder.
This means that the immune system mistakenly attacks its own healthy central nervous system tissue. The resulting damage to the central nervous system interferes with the transmission of nerve signals between the brain and spinal cord and other parts of the body. This causes the symptoms of MS. Multiple sclerosis (MS) is a long-term (chronic) central nervous system disease.
It's thought to be an autoimmune disorder, a condition in which the body attacks itself by mistake. Multiple sclerosis is an unpredictable disease that affects people differently. Some people with multiple sclerosis may have only mild symptoms. Others may lose the ability to see clearly, write, speak, or walk when communication between the brain and other parts of the body is interrupted.
Multiple sclerosis (MS) is a chronic disease of the central nervous system. Some people may be only mildly affected. Others may lose the ability to see clearly, write, speak, or walk. Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that can affect the brain, spinal cord, and optic nerves.
Pain is rarely the first sign of multiple sclerosis, but pain often occurs with optic neuritis and trigeminal neuralgia, a disorder that affects one of the nerves that provides sensitivity to different parts of the face. The autoimmune model of the pathogenesis of multiple sclerosis (MS) provided for many years a useful but incomplete conceptual framework for understanding the complex range of factors that lead to the loss of immune homeostasis, axonal and myelin injury, and the progression of neurological symptoms. Trigeminal neuralgia (facial pain) is treated with anticonvulsant or antispasmodic drugs or, less commonly, with pain relievers. Before conducting any clinical trial, the drugs in question must be studied in larger animal models that more closely resemble human physiological and anatomical structures, and their results must be acceptable.
Foreign agents can have a nuclear antigen that is structurally homologous with components of the myelin sheet, such as the proteolipid protein, the myelin basic protein and the myelin-associated glycoprotein. Research shows that a healthy diet, exercise, non-smoking, ongoing preventive care, and treatment for other medical conditions can also affect the progression and life expectancy of MS. Multiple sclerosis is an immune-mediated disease in which the body's immune system mistakenly attacks myelin. Folic acid taken before conception and for at least the first 4 weeks of pregnancy can prevent about 7 out of 10 cases of neural tube defects.
The term multiple sclerosis refers to the distinctive areas of scar tissue (sclerosis also called plaques or lesions) that result from an attack on myelin by the immune system. Multiple sclerosis (MS) is the most common disabling neurological disease among young adults, and symptoms usually appear between the ages of 20 and 40. Researchers in the BEAT-MS clinical trial (the best available therapy against autologous hematopoietic stem cell transplantation for multiple sclerosis) are extracting some immune cells and then injecting some of the person's own blood-producing stem cells to restore the immune system and stop attacking the CNS. If you or a loved one has been diagnosed with multiple sclerosis, you probably have a lot of questions.
Depression can range from feeling depressed or having negative thoughts to the most serious form of clinical depression that can last for months and affect your daily life. These symptoms may be mild and go unnoticed by others, or they may be more serious and begin to affect employment, social interactions, and relationships. .
